Description

4-(3-Formyl-9-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-2-Yl)-Piperazine-1-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of novel, complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex heterocyclic APIs, particularly in oncology and CNS therapeutic areas.
• Drug Discovery Research: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Serves as a key reactant for constructing fused pyrimidine and piperazine-containing molecular architectures.
• Process Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs).
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying novel organic reactions and heterocyclic chemistry.

Basic Information

Product Name	4-(3-Formyl-9-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-2-Yl)-Piperazine-1-Carboxylic Acid Ethyl Ester
CAS No.	850159-68-1
Molecular Formula	C17H18N4O4
Molecular Weight	342.35 g/mol
Synonyms	Ethyl 4-(3-formyl-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)piperazine-1-carboxylate; 4H-Pyrido[1,2-a]pyrimidine-2-piperazinecarboxylic acid, 3-formyl-9-methyl-4-oxo-, ethyl ester; 850159-68-1; Ethyl 4-(3-formyl-9-methyl-4-oxopyrido[1,2-a]pyrimidin-2-yl)piperazine-1-carboxylate; 2-Piperazinecarboxylic acid, 4-(3-formyl-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-(3-Formyl-9-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-2-Yl)-Piperazine-1-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP starting material applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.