Description

Fmoc-Lys(Boc)-Oh-13C6,15N2 is a high-purity, isotopically labeled derivative of the amino acid lysine, specifically designed for advanced research and development. This compound is essential for applications requiring precise tracking and quantification in complex biological systems, offering unparalleled accuracy in mass spectrometry and metabolic studies. It is a critical building block for pharmaceutical researchers, proteomics scientists, and diagnostic developers working on peptide-based therapeutics, biomarker discovery, and pharmacokinetic analysis.

Application

• Internal Standard for Quantitative Mass Spectrometry (MS): Used as a stable isotope-labeled internal standard for the absolute quantification of peptides and proteins in LC-MS/MS workflows.
• Metabolic Pathway Tracing: Enables the study of protein synthesis, degradation, and turnover rates in cell culture and in vivo models due to its 13C and 15N labels.
• Peptide Synthesis (SPPS): Serves as a protected, labeled amino acid building block in solid-phase peptide synthesis for creating isotopically tagged peptides.
• Proteomics Research: Critical for SILAC (Stable Isotope Labeling by Amino acids in Cell culture) and other quantitative proteomics techniques to compare protein expression levels.
• Biomarker Discovery & Validation: Facilitates the accurate measurement of low-abundance peptides and proteins in biological fluids for diagnostic development.
• Pharmaceutical R&D: Employed in the development and analysis of peptide-based drugs, including ADME (Absorption, Distribution, Metabolism, Excretion) studies.

Basic Information

Product Name	Fmoc-Lys(Boc)-Oh-13C6,15N2
CAS No.	850080-89-6
Molecular Formula	C27H3313C615N2O6
Molecular Weight	~529.6 g/mol (for labeled form)
Synonyms	Fmoc-L-lysine(Boc)-OH-13C6,15N2; Nα-Fmoc-Nε-Boc-L-lysine-13C6,15N2; Nα-(9-Fluorenylmethoxycarbonyl)-Nε-(tert-butoxycarbonyl)-L-lysine-13C6,15N2; Fmoc-Lys(Boc)-OH (U-13C6, 15N2); Stable Isotope Labeled Fmoc-Lys(Boc)-OH; (2S)-6-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid-13C6,15N2; Fmoc-Lys(Boc)-13C6,15N2-OH
EINECS	Contact for details

Quality Control

Every batch of Fmoc-Lys(Boc)-Oh-13C6,15N2 is manufactured and tested under strict quality management systems to ensure the highest isotopic and chemical purity for sensitive research applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and isotopic enrichment. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to expected mass
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C; ≥ 99 atom % 15N
Chemical Purity (NMR)	Conforms
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.