Description

5-Amino-4-Bromopyrimidine is a high-purity brominated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and amino functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: Serves as a handle for attaching fluorescent probes or other functional groups to biomolecules.
• Cross-Coupling Reactions: Valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Nucleic Acid Chemistry: Intermediate for the modification of nucleosides and the synthesis of non-natural base pairs.

Basic Information

Item	Detail
Product Name	5-Amino-4-Bromopyrimidine
CAS No.	849353-34-0
Molecular Formula	C4H4BrN3
Molecular Weight	174.00 g/mol
Synonyms	4-Bromo-5-pyrimidinamine; 4-Bromo-5-aminopyrimidine; 5-Amino-4-bromopyrimidine; 5-Pyrimidinamine, 4-bromo-; 849353-34-0; 4-Bromopyrimidin-5-amine
EINECS	Contact for details

Quality Control

Our 5-Amino-4-Bromopyrimidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.