Description

4-({[4-(Pyridin-3-Yl)Pyrimidin-2-Yl]Amino}Methyl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of targeted small-molecule therapeutics, particularly kinase inhibitors. Pharmaceutical R&D and manufacturing organizations need it to develop and produce novel drug candidates for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology research and drug development.
• Biochemical Research: Used as a reference standard or active compound in enzymatic assays and biological pathway studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final chemical structure of investigational new drugs (INDs).
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of clinical trial materials and commercial APIs.
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and drug discovery.

Basic Information

Item	Detail
Product Name	4-({[4-(Pyridin-3-Yl)Pyrimidin-2-Yl]Amino}Methyl)Benzoic Acid
CAS No.	849235-68-3
Molecular Formula	C17H14N4O2
Molecular Weight	306.32 g/mol
Synonyms	4-[[[4-(3-Pyridinyl)-2-pyrimidinyl]amino]methyl]benzoic acid; 4-({[4-(3-Pyridyl)pyrimidin-2-yl]amino}methyl)benzoic acid; Benzoic acid, 4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]-; 849235-68-3; 4-({[4-(Pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-({[4-(Pyridin-3-Yl)Pyrimidin-2-Yl]Amino}Methyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.