Description

4-[(5-Bromopyrimidin-2-Yl)Thio]Aniline is a high-purity, advanced pharmaceutical intermediate featuring a bromopyrimidine-thioaniline core structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel small molecule therapeutics. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and cellular signaling pathways.
• Agrochemical Research: Serves as a building block for developing novel active ingredients in crop protection research.
• Material Science: Potential use in the synthesis of specialized organic electronic materials and ligands for catalysis.

Basic Information

Product Name	4-[(5-Bromopyrimidin-2-Yl)Thio]Aniline
CAS No.	849235-61-6
Molecular Formula	C10H7BrN4S
Molecular Weight	295.16 g/mol
Synonyms	4-[(5-Bromopyrimidin-2-yl)sulfanyl]aniline; 4-[(5-Bromo-2-pyrimidinyl)thio]benzenamine; 4-Amino phenyl 5-bromopyrimidin-2-yl sulfide; 5-Bromo-2-((4-aminophenyl)thio)pyrimidine; Benzenamine, 4-[(5-bromo-2-pyrimidinyl)thio]-; 849235-61-6; 4-(5-Bromopyrimidin-2-ylthio)aniline
EINECS	Contact for details

Quality Control

Every batch of 4-[(5-Bromopyrimidin-2-Yl)Thio]Aniline is manufactured under strict quality management systems and undergoes comprehensive analytical testing. Our products are produced to meet the stringent requirements of pharmaceutical R&D, with typical purity levels exceeding 97% (HPLC). A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.