Description

5-Nitro-2-(4-Pyrimidin-2-Ylpiperazin-1-Yl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound is valued for its role as a critical building block in the research and development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds. The material's specific structure makes it essential for projects targeting specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) research.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists to explore structure-activity relationships (SAR) in new molecular entities.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step manufacturing process of complex target molecules for preclinical and clinical studies.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for analytical method development and validation.
• Fine Chemical Production: Integral to the custom synthesis of high-value, low-volume specialty chemicals for advanced applications.

Basic Information

Product Name	5-Nitro-2-(4-Pyrimidin-2-Ylpiperazin-1-Yl)Benzonitrile
CAS No.	849043-40-9
Molecular Formula	C15H13N7O2
Molecular Weight	323.31 g/mol
Synonyms	5-Nitro-2-[4-(pyrimidin-2-yl)piperazin-1-yl]benzonitrile; 2-[4-(2-Pyrimidinyl)-1-piperazinyl]-5-nitrobenzonitrile; Benzonitrile, 5-nitro-2-[4-(2-pyrimidinyl)-1-piperazinyl]-; 849043-40-9; 5-Nitro-2-(4-pyrimidin-2-yl-piperazin-1-yl)-benzonitrile; 5-Nitro-2-(4-(pyrimidin-2-yl)piperazin-1-yl)benzonitrile
EINECS	Contact for details

Quality Control

Our 5-Nitro-2-(4-Pyrimidin-2-Ylpiperazin-1-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.