Description

2-[(5-Bromopyrimidin-2-Yl)Thio]Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its unique bromopyrimidine-thioaniline structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Agrochemical Research: Used in the development of novel fungicides and herbicides, leveraging its heterocyclic activity.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes to study enzyme function and cellular pathways.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with specific electronic or optical properties.
• Academic & Contract Research: Employed in universities and CROs for method development and novel synthetic route exploration.

Basic Information

Product Name	2-[(5-Bromopyrimidin-2-Yl)Thio]Aniline
CAS No.	849021-43-8
Molecular Formula	C10H7BrN4S
Molecular Weight	295.16 g/mol
Synonyms	2-[(5-Bromopyrimidin-2-yl)sulfanyl]aniline; 2-Amino-1-[(5-bromopyrimidin-2-yl)thio]benzene; 5-Bromo-2-[(2-aminophenyl)thio]pyrimidine; 2-[(5-Bromo-2-pyrimidinyl)thio]benzenamine; Benzenamine, 2-[(5-bromo-2-pyrimidinyl)thio]-; 849021-43-8; 2-(5-Bromopyrimidin-2-ylthio)aniline
EINECS	Contact for details

Quality Control

Our 2-[(5-Bromopyrimidin-2-Yl)Thio]Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.