Description

2-[4-(5-Bromopyrimidin-2-Yl)Piperazin-1-Yl]Ethanol is a high-purity, functionalized heterocyclic building block designed for advanced chemical synthesis. This compound is critical for research and development in pharmaceutical discovery, offering a versatile scaffold for creating novel active molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and target engagement.
• Agrochemical Development: Intermediate in the research and synthesis of novel crop protection agents.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for CDMOs and fine chemical suppliers producing custom APIs and advanced intermediates.

Basic Information

Product Name	2-[4-(5-Bromopyrimidin-2-Yl)Piperazin-1-Yl]Ethanol
CAS No.	849021-42-7
Molecular Formula	C10H14BrN5O
Molecular Weight	300.16 g/mol
Synonyms	5-Bromo-2-(4-(2-hydroxyethyl)piperazin-1-yl)pyrimidine; 2-(4-(5-Bromopyrimidin-2-yl)piperazin-1-yl)ethan-1-ol; 5-Bromo-2-[1-piperazinyl]pyrimidine ethanol; 849021-42-7; 5-Bromo-2-(4-(2-hydroxyethyl)-1-piperazinyl)pyrimidine; 2-(4-(5-Bromopyrimidin-2-yl)piperazin-1-yl)ethanol
EINECS	Contact for details

Quality Control

Our 2-[4-(4-(5-Bromopyrimidin-2-Yl)Piperazin-1-Yl]Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.