Description

1-(4-tert-Butylphenyl)-2-Pyrimidin-4-Ylethanone is a high-purity organic compound featuring a pyrimidine core linked to a tert-butylphenyl ketone moiety. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for fine chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to construct complex molecules for new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Serves as a precursor for developing new generations of herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrimidine ring.
• Material Science: Used in the research and development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Acts as a versatile synthon for organic chemists to create more complex heterocyclic compounds through reactions like cross-coupling, cyclization, and functional group transformations.
• Life Science Reagents: Employed in biochemical research as a scaffold or inhibitor probe for studying enzyme kinetics and protein-ligand interactions.

Basic Information

Product Name	1-(4-tert-Butylphenyl)-2-Pyrimidin-4-Ylethanone
CAS No.	849021-29-0
Molecular Formula	C₁₆H₁₈N₂O
Molecular Weight	254.33 g/mol
Synonyms	4'-tert-Butyl-4-pyrimidinylacetophenone; 1-(4-(tert-Butyl)phenyl)-2-(pyrimidin-4-yl)ethan-1-one; 4-(2-(4-tert-Butylphenyl)-2-oxoethyl)pyrimidine; 849021-29-0; 4'-tert-Butyl-4-pyrimidinyl acetophenone; 2-(4-tert-Butylphenyl)-1-(pyrimidin-4-yl)ethanone; 1-(4-tert-butylphenyl)-2-(4-pyrimidinyl)ethanone
EINECS	Contact for details

Quality Control

Our production of 1-(4-tert-Butylphenyl)-2-Pyrimidin-4-Ylethanone adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.