Description

Ethanone, 1-(2-Amino-4,6-Dichloro-5-Pyrimidinyl)- is a high-purity pyrimidine derivative building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific chlorinated amino-pyrimidine structure enables precise molecular modifications. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and kinase inhibitor research.
• Agrochemical Synthesis: Used as a precursor for developing advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Specialty Fine Chemicals: Intermediate in the production of dyes, pigments, and other performance chemicals requiring a dichloropyrimidine core.
• Material Science: Potential monomer or precursor for synthesizing specialized polymers and organic electronic materials.

Basic Information

Product Name	Ethanone, 1-(2-Amino-4,6-Dichloro-5-Pyrimidinyl)-
CAS No.	848697-05-2
Molecular Formula	C6H5Cl2N3O
Molecular Weight	206.03 g/mol
Synonyms	1-(2-Amino-4,6-dichloropyrimidin-5-yl)ethanone; 2-Amino-4,6-dichloro-5-acetylpyrimidine; 5-Acetyl-2-amino-4,6-dichloropyrimidine; 4,6-Dichloro-2-amino-5-acetylpyrimidine; 1-(2-Amino-4,6-dichloro-5-pyrimidinyl)ethanone; 5-Pyrimidinyl, 2-amino-4,6-dichloro-, 1-ethanone; CAS 848697-05-2
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2-Amino-4,6-Dichloro-5-Pyrimidinyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Production adheres to cGMP guidelines where applicable. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.