Description

4-Bromo-7H-Pyrrolo[2,3-d]pyrimidin-2-amine is a high-purity, heterocyclic organic building block of significant importance in modern pharmaceutical and agrochemical research. Its core value lies in its functionalized pyrrolopyrimidine scaffold, which serves as a versatile intermediate for the synthesis of more complex molecules targeting various biological pathways. This compound is primarily needed by research scientists and process chemists in the pharmaceutical industry for the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitors, particularly for oncology and inflammatory disease targets.
• Agrochemical Research: Used in the discovery and synthesis of novel active ingredients for crop protection products.
• Chemical Biology: Serves as a valuable probe or building block in the study of enzyme function and cellular signaling pathways.
• Organic Synthesis: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization campaigns.
• Bioconjugation: The reactive bromo and amine groups allow for further functionalization and conjugation in biopharmaceutical applications.

Basic Information

Product Name	4-Bromo-7H-Pyrrolo[2,3-d]pyrimidin-2-amine
CAS No.	848694-32-6
Molecular Formula	C6H5BrN4
Molecular Weight	213.04 g/mol
Synonyms	2-Amino-4-bromo-7H-pyrrolo[2,3-d]pyrimidine; 4-Bromo-7H-pyrrolo[2,3-d]pyrimidin-2-ylamine; 4-Bromo-2-amino-7H-pyrrolo[2,3-d]pyrimidine; 4-Bromo-2-aminopyrrolo[2,3-d]pyrimidine; 848694-32-6; 4-Bromo-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 4-Bromo-2-aminopyrrolopyrimidine
EINECS	Contact for details

Quality Control

Our 4-Bromo-7H-Pyrrolo[2,3-d]pyrimidin-2-amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.