Description

5-(3,4-Dimethylphenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its core value lies in its unique molecular architecture, which combines a pyrazolopyrimidine core with a trifluoromethyl group and a carboxylic acid handle, enabling precise structural modifications. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Serves as a critical building block for creating next-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the development of advanced organic electronic materials, such as OLEDs or charge-transport layers, due to its conjugated system.
• Chemical Biology Probe Development: Employed to synthesize molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific R&D programs.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	5-(3,4-Dimethylphenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	848436-25-9
Molecular Formula	C₁₇H₁₂F₃N₃O₂
Molecular Weight	347.29 g/mol
Synonyms	7-(Trifluoromethyl)-5-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 5-(3,4-Dimethylphenyl)-7-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 5-(3,4-dimethylphenyl)-7-(trifluoromethyl)-; 848436-25-9; AKOS025311193; ZINC000257830509; SCHEMBL23306296; DTXSID60677669
EINECS	Contact for details

Quality Control

Every batch of 5-(3,4-Dimethylphenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards for pharmaceutical and agrochemical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.