Description

5-(4-Methoxy-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-3-Carbonyl Chloride is a high-value, multi-functional chemical building block designed for advanced synthetic chemistry. This compound is critical for research and development in pharmaceutical and agrochemical sectors, where its unique pyrazolopyrimidine core and reactive carbonyl chloride group enable the creation of novel active ingredients. It is primarily sought after by R&D chemists and process development scientists working on new drug candidates, crop protection agents, and other fine chemical intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel kinase inhibitors, anti-cancer agents, and other small molecule therapeutics.
• Agrochemical Research: Used in developing advanced fungicides, herbicides, and insecticides with improved efficacy and selectivity.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating labeled compounds and molecular probes for target identification and validation studies.
• Material Science Precursor: Potential intermediate for synthesizing organic electronic materials and specialty polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific advanced intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	5-(4-Methoxy-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-3-Carbonyl Chloride
CAS No.	848422-75-3
Molecular Formula	C15H9ClF3N3O2
Molecular Weight	355.70 g/mol
Synonyms	5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride; 7-Trifluoromethyl-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride; 848422-75-3; Pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride, 5-(4-methoxyphenyl)-7-(trifluoromethyl)-; 5-(p-Methoxyphenyl)-7-trifluoromethylpyrazolo[1,5-a]pyrimidine-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-(4-Methoxy-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-3-Carbonyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles via validated methods such as HPLC, NMR, and LC-MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.