Description

n-Tetradecanoyl-4-Hydroxy-L-Proline is a specialized proline derivative where the amino acid is acylated with a myristoyl (tetradecanoyl) chain. This chemical modification is significant for enhancing lipophilicity and membrane permeability, making it a valuable building block in advanced pharmaceutical and biochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, cosmetic, and peptide synthesis industries for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting metabolic disorders or requiring enhanced bioavailability.
• Peptide Chemistry & Modification: Used to introduce lipophilic moieties into peptide sequences to improve stability, cell penetration, and pharmacokinetic properties.
• Cosmetic Actives Development: Serves as a synthetic intermediate for creating bioactive ingredients in anti-aging and skin-repair formulations.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and proteomics research to investigate protein-lipid interactions.
• Surfactant & Lipid Science: Acts as a model compound or synthetic building block in the study of novel amphiphilic molecules and lipid membrane systems.

Basic Information

Product Name	n-Tetradecanoyl-4-Hydroxy-L-Proline
CAS No.	848390-99-8
Molecular Formula	C19H33NO4
Molecular Weight	339.47 g/mol
Synonyms	Myristoyl-4-hydroxy-L-proline; L-Proline, 4-hydroxy-1-(1-oxotetradecyl)-; 4-Hydroxy-1-tetradecanoyl-L-proline; 1-Myristoyl-4-hydroxy-L-proline; Tetradecanoylhydroxyproline; N-Myristoyl-4-hydroxy-L-proline; 4-Hydroxy-N-tetradecanoyl-L-proline; N-(Tetradecanoyl)-4-hydroxy-L-proline
EINECS	Contact for details

Quality Control

Our n-Tetradecanoyl-4-Hydroxy-L-Proline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.