Description

Ethyl 6-Methyl-4-Oxo-1,4-Dihydrofuro[2,3-D]Pyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic compound class. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for its role as a key building block.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel furopyrimidine-based drug candidates.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential new chemical entities (NCEs).
• Academic Research: Utilized in university and institutional labs for heterocyclic chemistry studies and methodology development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	Ethyl 6-Methyl-4-Oxo-1,4-Dihydrofuro[2,3-D]Pyrimidine-5-Carboxylate
CAS No.	848316-19-8
Molecular Formula	C₁₀H₁₀N₂O₄
Molecular Weight	222.20 g/mol
Synonyms	Ethyl 6-methyl-4-oxo-1,4-dihydrofuro[2,3-d]pyrimidine-5-carboxylate; 6-Methyl-4-oxo-1,4-dihydrofuro[2,3-d]pyrimidine-5-carboxylic acid ethyl ester; Furo[2,3-d]pyrimidine-5-carboxylic acid, 1,4-dihydro-6-methyl-4-oxo-, ethyl ester; Ethyl 6-methyl-4-oxo-4H-furo[2,3-d]pyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 6-Methyl-4-Oxo-1,4-Dihydrofuro[2,3-D]Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.