Description

4-(6-Acetyl-1,3,7-Trimethyl-2,4-Dioxo-1,2,3,4,5,8-Hexahydropyrido[2,3-D]Pyrimidin-5-Yl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and other disease areas targeting specific enzymatic pathways. It is essential for pharmaceutical R&D laboratories, fine chemical synthesis units, and contract manufacturing organizations (CMOs) engaged in producing next-generation active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapies.
• Oncology Research: Used in the development and preclinical testing of novel anti-cancer compounds due to its specific molecular scaffold.
• Biochemical Research: Acts as a reference standard or a tool compound in enzymatic assays and biological pathway studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing sophisticated nitrogen-containing heterocycles.
• Contract Manufacturing: Supplied to CMOs and CDMOs for the cGMP production of investigational new drugs (INDs) and new drug applications (NDAs).
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and novel compound library generation.

Basic Information

Product Name	4-(6-Acetyl-1,3,7-Trimethyl-2,4-Dioxo-1,2,3,4,5,8-Hexahydropyrido[2,3-D]Pyrimidin-5-Yl)Benzoic Acid
CAS No.	848029-08-3
Molecular Formula	C21H21N3O5
Molecular Weight	395.41 g/mol
Synonyms	4-[(6-Acetyl-1,3,7-trimethyl-2,4-dioxo-1,2,3,4,5,8-hexahydropyrido[2,3-d]pyrimidin-5-yl)]benzoic acid; 5-(4-Carboxyphenyl)-6-acetyl-1,3,7-trimethyl-1,2,3,4,5,8-hexahydropyrido[2,3-d]pyrimidine-2,4-dione; Benzoic acid, 4-(6-acetyl-1,3,7-trimethyl-2,4-dioxo-1,2,3,4,5,8-hexahydropyrido[2,3-d]pyrimidin-5-yl)-; CAS 848029-08-3
EINECS	Contact for details

Quality Control

Our 4-(6-Acetyl-1,3,7-Trimethyl-2,4-Dioxo-1,2,3,4,5,8-Hexahydropyrido[2,3-D]Pyrimidin-5-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.