Description

2-Bis(tert-Butoxycarbonyl)Amino-4,6-Dichloropyrimidine is a high-value, protected pyrimidine derivative used as a critical building block in advanced organic synthesis. Its primary importance lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleoside and nucleotide analogs for antiviral and anticancer drug candidates.
• Agrochemical Research: Used in the development of novel pyrimidine-based herbicides and fungicides.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) groups serve as protective groups for amines in multi-step synthetic sequences.
• Material Science: Precursor for the synthesis of functionalized heterocyclic compounds used in organic electronic materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Bis(tert-Butoxycarbonyl)Amino-4,6-Dichloropyrimidine
CAS No.	847675-82-5
Molecular Formula	C₁₄H₂₀Cl₂N₄O₄
Molecular Weight	379.24 g/mol
Synonyms	2,4-Dichloro-6-[bis[(2-methylpropan-2-yl)oxycarbonyl]amino]pyrimidine; 2-[Bis(tert-butoxycarbonyl)amino]-4,6-dichloropyrimidine; 4,6-Dichloro-2-[bis(tert-butoxycarbonyl)amino]pyrimidine; 2-(Di-Boc-amino)-4,6-dichloropyrimidine; 2-(Bis-Boc-amino)-4,6-dichloropyrimidine; 2-Amino-4,6-dichloropyrimidine, N,N-bis(tert-butoxycarbonyl)-; N,N-Bis(tert-butoxycarbonyl)-4,6-dichloropyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 2-Bis(tert-Butoxycarbonyl)Amino-4,6-Dichloropyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.