Description

7-[3,5-Bis-o-[(2,4-Dichlorophenyl)Methyl]-2-C-Methyl-β-D-Ribofuranosyl]-4-Chloro-5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine is a sophisticated nucleoside analog building block of significant interest in advanced pharmaceutical research and development. Its complex, multi-functionalized structure makes it a critical intermediate for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. This high-purity compound is essential for medicinal chemists and R&D teams in pharmaceutical and biotechnology companies seeking to develop next-generation targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel nucleoside-based antiviral and anticancer drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the biological activity and pharmacokinetic properties of new chemical entities.
• Biochemical Probe Development: Acts as a substrate or inhibitor in enzymatic studies to investigate biological pathways and mechanisms of disease.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis, chemical biology, and drug discovery.

Basic Information

Product Name	7-[3,5-Bis-o-[(2,4-Dichlorophenyl)Methyl]-2-C-Methyl-β-D-Ribofuranosyl]-4-Chloro-5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	847551-25-1
Molecular Formula	C26H21Cl3IN3O4
Molecular Weight	704.73 g/mol
Synonyms	4-Chloro-5-iodo-7-[3,5-bis-O-[(2,4-dichlorophenyl)methyl]-2-C-methyl-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 7-[3,5-bis-O-[(2,4-dichlorophenyl)methyl]-2-C-methyl-β-D-ribofuranosyl]-4-chloro-5-iodo-; CAS 847551-25-1; Nucleoside Analog Intermediate; Chloro-iodo pyrrolopyrimidine ribofuranosyl derivative.
EINECS	Contact for details

Quality Control

Our 7-[3,5-Bis-o-[(2,4-Dichlorophenyl)Methyl]-2-C-Methyl-β-D-Ribofuranosyl]-4-Chloro-5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.