Description

2,4-Difluoro-3-Methylbenzaldehyde is a versatile fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the aldehyde functional group, which enable precise molecular modifications to enhance the properties of target compounds. This high-purity intermediate is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can improve metabolic stability, bioavailability, and activity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to modify polarity and mesomorphic properties.
• Organic Electronic Materials: Employed in the creation of novel organic semiconductors, charge-transport materials, and fluorophores for OLEDs and other optoelectronic devices.
• Cross-Coupling Reactions: The aldehyde group makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl systems.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination strategies and synthesizing specialized chemical libraries.

Basic Information

Product Name	2,4-Difluoro-3-Methylbenzaldehyde
CAS No.	847502-88-9
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	3-Methyl-2,4-difluorobenzaldehyde; 2,4-Difluoro-3-methyl-benzaldehyde; Benzaldehyde, 2,4-difluoro-3-methyl-; 3-Methyl-2,4-difluorobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3-Methylbenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets the stringent requirements for pharmaceutical and advanced material synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.