Description

1-(3,4-Difluoro-2-Methylphenyl)Methanamine is a high-purity, fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters because its unique difluoromethylphenyl scaffold provides a valuable handle for modulating the physicochemical and metabolic properties of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, where its structure serves as a key intermediate.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated nature.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated aromatic amines.

Basic Information

Product Name	1-(3,4-Difluoro-2-Methylphenyl)Methanamine
CAS No.	847502-85-6
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	(3,4-Difluoro-2-methylphenyl)methanamine; 1-(3,4-Difluoro-2-methylphenyl)methanamine; 2-Methyl-3,4-difluorobenzylamine; 3,4-Difluoro-2-methylbenzylamine; α-Amino-3,4-difluoro-2-methyltoluene; Benzenemethanamine, 3,4-difluoro-2-methyl-; 847502-85-6; 1-(3,4-Difluoro-2-methylphenyl)methanamine
EINECS	Contact for details

Quality Control

Our 1-(3,4-Difluoro-2-Methylphenyl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider storing under an inert atmosphere such as nitrogen to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.