Description

n-[3-Cyano-1-(3-Isopropoxypropyl)-5-Oxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidin-2-Ylidene]-2-Methylbenzamide CAS NO 847368-29-0 is a high-purity, complex heterocyclic organic compound featuring a dipyridopyrimidinone core. This compound is valued as a key advanced intermediate in pharmaceutical research and development, particularly for its potential role in modulating specific biological targets. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and other therapeutic areas.
• Biochemical Research: Used as a reference standard or a probe compound in pharmacological and enzymatic studies to investigate structure-activity relationships (SAR).
• Chemical Synthesis: Acts as a versatile precursor for further chemical modifications to create libraries of compounds for high-throughput screening.
• Academic Research: Employed in university and institutional labs for fundamental research in medicinal chemistry and heterocyclic compound synthesis.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	n-[3-Cyano-1-(3-Isopropoxypropyl)-5-Oxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidin-2-Ylidene]-2-Methylbenzamide
CAS No.	847368-29-0
Molecular Formula	C27H25N5O3
Molecular Weight	467.52 g/mol
Synonyms	2-Methyl-N-[3-cyano-1-(3-isopropoxypropyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidin-2-ylidene]benzamide; UNII-9J5Q8Y8S0W; 9J5Q8Y8S0W; Benzamide, N-[3-cyano-1-(3-isopropoxypropyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidin-2-ylidene]-2-methyl-; CHEMBL3186662; BDBM50389378; AKOS009158966; ZINC000253914007
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes. We support development and commercial projects with material produced under quality guidelines suitable for non-GMP and cGMP applications as required.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.