Description

5-Butyl-2-Chloropyrimidine is a versatile halogenated pyrimidine derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• As a critical pharmaceutical intermediate in the synthesis of novel drug candidates, particularly kinase inhibitors and antiviral agents.
• Used in agrochemical research for the development of new herbicides, fungicides, and plant growth regulators.
• Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Employed in material science for the creation of specialized ligands, functional polymers, and organic electronic materials.
• Acts as a precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create more complex pyrimidine libraries.

Basic Information

Product Name	5-Butyl-2-Chloropyrimidine
CAS No.	847227-37-6
Molecular Formula	C8H11ClN2
Molecular Weight	170.64 g/mol
Synonyms	2-Chloro-5-butylpyrimidine; 5-n-Butyl-2-chloropyrimidine; 2-Chloro-5-n-butylpyrimidine; Pyrimidine, 2-chloro-5-butyl-; Butylchloropyrimidine
EINECS	Contact for details

Quality Control

Our 5-Butyl-2-Chloropyrimidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP guidelines for the production of pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.