Description

3-(4-Fluorobenzyloxy)-Bromobenzene is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorobenzyloxy moiety enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens, which are essential components in display technologies.
• Organic Electronic Materials: Employed in the synthesis of charge-transport materials and emitters for OLED (Organic Light-Emitting Diode) applications.
• Catalyst Ligand Development: The bromo and ether functionalities allow for further derivatization to create specialized ligands for transition metal catalysis.
• Chemical Research & Development: A versatile scaffold for exploring new chemical reactions and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	3-(4-Fluorobenzyloxy)-Bromobenzene
CAS No.	845866-52-6
Molecular Formula	C₁₃H₁₀BrFO
Molecular Weight	281.12 g/mol
Synonyms	1-Bromo-3-[(4-fluorophenyl)methoxy]benzene; 3-Bromophenyl 4-Fluorobenzyl Ether; 4-Fluorobenzyl 3-Bromophenyl Ether; 3-Bromo-1-[(4-fluorobenzyl)oxy]benzene; 3-Bromophenyl 4-Fluorobenzyl Ether; (3-Bromophenoxy)methyl]-4-fluorobenzene; 845866-52-6; 3-(p-Fluorobenzyloxy)bromobenzene
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorobenzyloxy)-Bromobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in opaque secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.