Description

7-(4-Chlorophenyl)-3-(Naphthalen-1-Ylmethyl)-7H-Pyrazolo[4,3-E][1,2,4]Triazolo[4,3-C]Pyrimidine is a high-value, complex heterocyclic compound that serves as a critical building block in advanced pharmaceutical research and development. This molecule is of significant interest for its potential as a core scaffold in the design of novel therapeutic agents, particularly targeting protein kinases and other key biological pathways. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for lead optimization and preclinical studies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially for kinase inhibitors.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and target validation studies.
• Medicinal Chemistry: Serves as a privileged scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Process Chemistry: Employed in route scouting and scale-up optimization for the synthesis of complex active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and early-stage development services.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	7-(4-Chlorophenyl)-3-(Naphthalen-1-Ylmethyl)-7H-Pyrazolo[4,3-E][1,2,4]Triazolo[4,3-C]Pyrimidine
CAS No.	845800-29-5
Molecular Formula	C24H16ClN7
Molecular Weight	437.88 g/mol
Synonyms	7-(4-Chlorophenyl)-3-(naphthalen-1-ylmethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine; 7-(p-Chlorophenyl)-3-(1-naphthylmethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine; 845800-29-5; 7H-Pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine, 7-(4-chlorophenyl)-3-(1-naphthalenylmethyl)-; AKOS025310991; CS-W009767; FT-0775786; NS00023827
EINECS	Contact for details

Quality Control

Our 7-(4-Chlorophenyl)-3-(Naphthalen-1-Ylmethyl)-7H-Pyrazolo[4,3-E][1,2,4]Triazolo[4,3-C]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.