Description

4-Amino-2,6-Dichloropyrimidine-5-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its reactive amino, chloro, and cyano substituents. This compound is essential for the synthesis of complex molecules, offering a versatile scaffold for constructing diverse chemical libraries and active pharmaceutical ingredients. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for constructing heterocyclic compounds and exploring new chemical spaces in medicinal chemistry.
• Material Science: Potential building block for the synthesis of organic electronic materials, dyes, and pigments.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific functionalization on a pyrimidine core.

Basic Information

Item	Details
Product Name	4-Amino-2,6-Dichloropyrimidine-5-Carbonitrile
CAS No.	845727-69-7
Molecular Formula	C5H2Cl2N4
Molecular Weight	188.99 g/mol
Synonyms	5-Cyano-2,6-dichloropyrimidin-4-amine; 2,6-Dichloro-4-aminopyrimidine-5-carbonitrile; 4-Amino-2,6-dichloro-5-pyrimidinecarbonitrile; 4-Amino-2,6-dichloro-5-cyanopyrimidine; 2,6-Dichloro-5-cyano-4-pyrimidinamine; 4-Pyrimidinamine, 2,6-dichloro-5-cyano-; 845727-69-7
EINECS	Contact for details

Quality Control

Our 4-Amino-2,6-Dichloropyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and GMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.