Description

2-Bromo-1-Pyrimidin-4-Yl-Ethanone Hydrobromide is a high-purity, versatile brominated pyrimidine building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Employed as a molecular probe or a building block for PROTACs (Proteolysis Targeting Chimeras) and other bifunctional molecules.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Utilized in medicinal chemistry programs and process development for route scouting and optimization.

Basic Information

Product Name	2-Bromo-1-Pyrimidin-4-Yl-Ethanone Hydrobromide
CAS No.	845267-57-4
Molecular Formula	C6H6Br2N2O
Molecular Weight	305.93 g/mol
Synonyms	4-Pyrimidinyl 2-bromoethanone hydrobromide; 2-Bromo-1-(4-pyrimidinyl)ethanone hydrobromide; 1-(Pyrimidin-4-yl)-2-bromoethanone hydrobromide; 2-Bromo-4-pyrimidinylethanone HBr; 4-Acetylpyrimidine, 2-bromo-, hydrobromide; CAS 845267-57-4
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Pyrimidin-4-Yl-Ethanone Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.