Description

7-(4-Chloro-Phenyl)-7H-Pyrazolo[4,3-E][1,2,4]Triazolo[4,3-C]Pyrimidine-3-Thiol is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel therapeutic agents, particularly in oncology and immunology research. It is primarily needed by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers developing next-generation small molecule drugs. Its unique scaffold offers significant potential for creating targeted inhibitors and modulators.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• Biochemical Research: Used as a reference standard or probe molecule in enzymatic and cellular assays for drug discovery.
• Organic Synthesis Building Block: Serves as a versatile scaffold for medicinal chemists to create novel chemical libraries for high-throughput screening.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents due to its bioactive heterocyclic core.
• Academic Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) of fused triazolopyrimidine systems.

Basic Information

Product Name	7-(4-Chloro-Phenyl)-7H-Pyrazolo[4,3-E][1,2,4]Triazolo[4,3-C]Pyrimidine-3-Thiol
CAS No.	844853-96-9
Molecular Formula	C13H7ClN6S
Molecular Weight	314.76 g/mol
Synonyms	7-(4-Chlorophenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine-3-thiol; 7-(p-Chlorophenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine-3-thiol; 844853-96-9; 7-(4-Chlorophenyl)-7H-pyrazolo[4,3-e]v-triazolo[4,3-c]pyrimidine-3-thiol; 7-(4-Chlorophenyl)-3-mercapto-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine; 3-Mercapto-7-(4-chlorophenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
EINECS	Contact for details

Quality Control

Our 7-(4-Chloro-Phenyl)-7H-Pyrazolo[4,3-E][1,2,4]Triazolo[4,3-C]Pyrimidine-3-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.