Description

2-Chloro-5-Methoxypyrimidin-4(3H)-One is a high-purity pyrimidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its versatile halogenated and methoxylated structure, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific pyrimidine scaffolds.
• Material Science Research: Serves as a precursor for functionalized heterocyclic compounds used in organic electronic materials.
• Chemical Biology: Employed as a probe or linker in the development of biochemical tools and diagnostic agents.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-5-Methoxypyrimidin-4(3H)-One
CAS No.	844843-40-9
Molecular Formula	C5H5ClN2O2
Molecular Weight	160.56 g/mol
Synonyms	4(3H)-Pyrimidinone, 2-chloro-5-methoxy-; 2-Chloro-5-methoxy-4(3H)-pyrimidinone; 2-Chloro-5-methoxypyrimidin-4-ol; 5-Methoxy-2-chloropyrimidin-4(3H)-one; 2-Chloro-5-methoxypyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methoxypyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.