Description

5-Bromo-2-Chloro-4(3H)-Pyrimidinone is a halogenated pyrimidinone derivative, a versatile and high-value heterocyclic building block crucial for advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen functionalities into pyrimidine-based scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of potential drug candidates, including kinase inhibitors, antiviral agents, and anticancer compounds.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the pyrimidine core provides specific biological activity.
• Chemical Research & Development: Serves as a fundamental building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Material Science Precursor: Can be utilized in the synthesis of organic ligands for catalysts or functional materials with specialized electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific halogenated pyrimidine motifs.

Basic Information

Product Name	5-Bromo-2-Chloro-4(3H)-Pyrimidinone
CAS No.	844843-37-4
Molecular Formula	C4H2BrClN2O
Molecular Weight	209.43 g/mol
Synonyms	5-Bromo-2-chloro-3,4-dihydropyrimidin-4-one; 2-Chloro-5-bromo-4(3H)-pyrimidinone; 4(3H)-Pyrimidinone, 5-bromo-2-chloro-; 5-Bromo-2-chloro-4-hydroxypyrimidine; 5-Bromo-2-chloropyrimidin-4-ol; 5-Bromo-2-chloro-4-pyrimidinol
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-4(3H)-Pyrimidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.