Description

4-Chloro-3,3'-Difluorobenzhydro is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring precise molecular architecture for active ingredients, such as medicinal chemistry research and specialty chemical manufacturing, are the primary users of this material.

Application

• As a versatile pharmaceutical intermediate in the synthesis of novel drug candidates, particularly those targeting central nervous system disorders.
• Critical building block for agrochemical research, used in developing new-generation herbicides and pesticides with fluorinated motifs.
• Employed in material science for creating advanced polymers and liquid crystals with specific electronic properties.
• Used in organic light-emitting diode (OLED) research as a precursor for electron-transport materials.
• Serves as a key synthon in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl systems.
• Intermediate for fluorinated liquid crystals used in display technologies.

Basic Information

Product Name	4-Chloro-3,3'-Difluorobenzhydro
CAS No.	844683-62-1
Molecular Formula	C13H8ClF2
Molecular Weight	237.65 g/mol
Synonyms	4-Chloro-3,3'-difluorobenzhydrol; 1-(4-Chlorophenyl)-1-(3-fluorophenyl)-2,2,2-trifluoroethanol (Check Isomer); [1-(4-Chlorophenyl)-1-(3-fluorophenyl)]methanol; Benzhydrol, 4-chloro-3,3'-difluoro-; (4-Chloro-3-fluorophenyl)(3-fluorophenyl)methanol; 4-Chloro-α-(3-fluorophenyl)-3-fluorobenzenemethanol
EINECS	Contact for details

Quality Control

Our 4-Chloro-3,3'-Difluorobenzhydro is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.