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1-(3-Fluorophenyl)Propan-1-Amine Hydrochloride CAS NO 844470-86-6


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CAS No.:844470-86-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(3-Fluorophenyl)Propan-1-Amine Hydrochloride is a high-purity fluorinated amine hydrochloride salt, a key chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and production in pharmaceutical, agrochemical, and specialty chemical industries requiring precise, high-quality intermediates.

Application

  • Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
  • Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
  • Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis and homogeneous catalysis.
  • Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.
  • Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials where a fluorinated phenylpropylamine moiety is required.

Basic Information

Product Name 1-(3-Fluorophenyl)Propan-1-Amine Hydrochloride
CAS No. 844470-86-6
Molecular Formula C9H12FN•HCl
Molecular Weight 189.66 g/mol
Synonyms 1-(3-Fluorophenyl)-1-propanamine hydrochloride; 1-Amino-1-(3-fluorophenyl)propane hydrochloride; 3-Fluoro-α-ethylbenzylamine hydrochloride; (R/S)-1-(3-Fluorophenyl)propylamine hydrochloride; 1-(3-Fluorophenyl)propan-1-amine HCl; 3-Fluoro-α-methylphenethylamine hydrochloride; Benzenemethanamine, 3-fluoro-α-ethyl-, hydrochloride
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Quality Control

Our 1-(3-Fluorophenyl)Propan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Chiral Purity (Chiral HPLC) ≥99.0% ee (or as specified)
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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