Description

2-Imino-1-(3-Isopropoxypropyl)-8-Methyl-5-Oxo-n-(2-Phenylethyl)-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidine-3-Carboxamide is a high-purity, complex heterocyclic compound serving as a critical advanced intermediate in pharmaceutical research and development. Its intricate fused-ring structure makes it a valuable building block for synthesizing novel therapeutic agents, particularly in oncology and targeted drug discovery. This compound is essential for medicinal chemists and R&D departments in pharmaceutical and biotechnology companies seeking to develop new small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Employed in the synthesis of potential anti-cancer compounds due to its dipyridopyrimidine core, which is common in many kinase-targeting drugs.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Imino-1-(3-Isopropoxypropyl)-8-Methyl-5-Oxo-n-(2-Phenylethyl)-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidine-3-Carboxamide
CAS No.	844451-21-4
Molecular Formula	C28H31N5O3
Molecular Weight	485.58 g/mol
Synonyms	2-Imino-1-(3-isopropoxypropyl)-8-methyl-5-oxo-N-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide; Dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide, 1,5-dihydro-2-imino-1-(3-(1-methylethoxy)propyl)-8-methyl-5-oxo-N-(2-phenylethyl)-; UNII-6Q8F0I5W8F; 6Q8F0I5W8F; CAS 844451-21-4
EINECS	Contact for details

Quality Control

Our 2-Imino-1-(3-Isopropoxypropyl)-8-Methyl-5-Oxo-n-(2-Phenylethyl)-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidine-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.