Description

8-[(2-Aminoethyl)Amino]-7-(2,4-Dichlorobenzyl)-1,3-Dimethyl-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, synthetically derived xanthine derivative with a unique chemical structure that serves as a critical building block in advanced pharmaceutical research and development. This compound matters because it provides a versatile scaffold for designing and synthesizing novel therapeutic agents, particularly in the fields of oncology and neurological disorders. Pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers are the primary entities that need this specialized intermediate to drive innovation in drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel adenosine receptor antagonists and phosphodiesterase (PDE) inhibitors.
• Drug Discovery Research: Used as a core scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies targeting central nervous system (CNS) diseases.
• Oncology Research: Investigated as a building block for potential anti-cancer agents due to its purine-based structure, which can interfere with cellular signaling pathways.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to understand the role of specific enzymatic targets and receptor subtypes.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, low-volume active pharmaceutical ingredients (APIs).
• Academic Research: Supplied to universities and research institutes for fundamental studies in organic chemistry and pharmacology.

Basic Information

Product Name	8-[(2-Aminoethyl)Amino]-7-(2,4-Dichlorobenzyl)-1,3-Dimethyl-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	843622-94-6
Molecular Formula	C₁₇H₁₉Cl₂N₇O₂
Molecular Weight	424.29 g/mol
Synonyms	8-[(2-Aminoethyl)amino]-7-[(2,4-dichlorophenyl)methyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 1H-Purine-2,6-dione, 8-[(2-aminoethyl)amino]-7-[(2,4-dichlorophenyl)methyl]-1,3-dimethyl-3,7-dihydro-; 843622-94-6; 8-(2-Aminoethylamino)-7-(2,4-dichlorobenzyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; N-(2-Aminoethyl)-7-(2,4-dichlorobenzyl)-1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purine-8-amine
EINECS	Contact for details

Quality Control

Our 8-[(2-Aminoethyl)Amino]-7-(2,4-Dichlorobenzyl)-1,3-Dimethyl-3,7-Dihydro-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS, IR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants and maintaining an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.