Description

(R)-1-(4-Bromo-Phenyl)-2,2,2-Trifluoro-Ethylamine is a high-purity chiral amine building block of significant importance in advanced organic synthesis. Its core value lies in its unique trifluoromethyl and bromophenyl groups, which are critical for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and bioavailability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Potential building block for specialty polymers and advanced organic materials with unique electronic properties.
• Chemical Biology: Employed as a molecular probe or tag in medicinal chemistry and biochemical research.

Basic Information

Product Name	(R)-1-(4-Bromo-Phenyl)-2,2,2-Trifluoro-Ethylamine
CAS No.	843608-53-7
Molecular Formula	C8H7BrF3N
Molecular Weight	254.05 g/mol
Synonyms	(R)-1-(4-Bromophenyl)-2,2,2-trifluoroethanamine; (R)-α-(4-Bromophenyl)-2,2,2-trifluoroethylamine; (R)-4'-Bromo-α,α,α-trifluorophenethylamine; (R)-1-(p-Bromophenyl)-2,2,2-trifluoroethylamine; (R)-2,2,2-Trifluoro-1-(4-bromophenyl)ethanamine; (R)-TFA-4-Br-Ph-CH(NH2)CF3; (R)-Trifluoro(4-bromophenyl)ethylamine
EINECS	Contact for details

Quality Control

Our (R)-1-(4-Bromo-Phenyl)-2,2,2-Trifluoro-Ethylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.