Description

2-Morpholinopyrimidine-5-Carbaldehyde is a versatile heterocyclic building block characterized by its pyrimidine core functionalized with both a morpholine ring and an aldehyde group. This compound matters as a critical intermediate in modern organic synthesis, enabling the construction of complex molecular architectures for pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the development of new active ingredients, particularly in kinase inhibitor programs and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in oncology and antiviral research.
• Kinase Inhibitor Scaffold: Used in the design and development of potent and selective kinase inhibitors due to its privileged pyrimidine-morpholine structure.
• Agrochemical Research: Serves as a building block for creating new active ingredients in crop protection and pest management.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and cellular pathways.
• Material Science: Potential precursor for the synthesis of functionalized polymers or ligands for metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates under cGMP conditions.

Basic Information

Product Name	2-Morpholinopyrimidine-5-Carbaldehyde
CAS No.	842974-69-0
Molecular Formula	C9H11N3O2
Molecular Weight	193.20 g/mol
Synonyms	5-Formyl-2-morpholinopyrimidine; 2-Morpholin-4-ylpyrimidine-5-carbaldehyde; Pyrimidine-5-carboxaldehyde, 2-(4-morpholinyl)-; 2-(Morpholin-4-yl)pyrimidine-5-carbaldehyde; 842974-69-0; 2-Morpholin-4-yl-pyrimidine-5-carbaldehyde; 2-(4-Morpholinyl)-5-pyrimidinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Morpholinopyrimidine-5-Carbaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.