Description

4-Chloro-3'-Fluorobenzhydrol is a versatile fluorinated and chlorinated benzhydrol derivative, serving as a crucial chiral intermediate in advanced organic synthesis. Its molecular architecture makes it particularly valuable for constructing complex pharmacophores and fine-tuning material properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and chlorine substituents enhance biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated compounds used in electronic display technologies.
• Chiral Ligand & Catalyst Development: Employed in asymmetric synthesis to create chiral auxiliaries and catalysts for enantioselective reactions.
• Polymer Modification: Acts as a monomer or modifier to introduce specific functional groups into polymer chains, altering thermal and chemical resistance.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and reduction reactions.

Basic Information

Product Name	4-Chloro-3'-Fluorobenzhydrol
CAS No.	842140-66-3
Molecular Formula	C₁₃H₁₀ClFO
Molecular Weight	236.67 g/mol
Synonyms	(4-Chlorophenyl)(3-fluorophenyl)methanol; 1-(4-Chlorophenyl)-1-(3-fluorophenyl)methanol; α-(4-Chlorophenyl)-3-fluorobenzyl alcohol; Benzhydrol, 4-chloro-3'-fluoro-; 3-Fluoro-4'-chlorobenzhydrol; (3-Fluorophenyl)(4-chlorophenyl)carbinol
EINECS	Contact for details

Quality Control

Our 4-Chloro-3'-Fluorobenzhydrol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.