Description

4-(2-Chloro-4-Fluorophenyl)Benzaldehyde is a high-purity aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique halogenated biphenyl structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it serves as a precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the halogenated phenyl groups for enhanced biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated and chlorinated aromatic cores used in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, refractive index, and chemical resistance properties.
• Organic Synthesis & Catalysis Research: A versatile reagent for cross-coupling reactions, such as Suzuki-Miyaura couplings, and as a substrate for studying new catalytic methodologies.
• Chemical Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-(2-Chloro-4-Fluorophenyl)Benzaldehyde
CAS No.	842140-45-8
Molecular Formula	C13H8ClFO
Molecular Weight	234.65 g/mol
Synonyms	4-(2-Chloro-4-fluorophenyl)benzaldehyde; 2-Chloro-4-fluorobiphenyl-4'-carboxaldehyde; [1,1'-Biphenyl]-4-carboxaldehyde, 2'-chloro-4'-fluoro-; 2'-Chloro-4'-fluoro[1,1'-biphenyl]-4-carboxaldehyde; 4-Formyl-2'-chloro-4'-fluorobiphenyl; (2-Chloro-4-fluorophenyl)benzaldehyde-4'; 842140-45-8; 4-(2-Chloro-4-fluorophenyl)benzenecarbaldehyde
EINECS	Contact for details

Quality Control

Our 4-(2-Chloro-4-Fluorophenyl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.