Description

6-(2-Bromoethyl)-1,3-Dimethyl-1H-Pyrrolo[3,4-D]Pyrimidine-2,4(3H,6H)-Dione is a high-value, heterocyclic organic building block featuring a reactive bromoethyl side chain. This compound is critical for medicinal chemistry research and development, serving as a versatile intermediate for the synthesis of novel pharmaceutical candidates. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its modifiable bromoethyl handle.
• Agrochemical Synthesis: Intermediate in the development of new active ingredients for crop protection.
• Chemical Biology Probes: Serves as a precursor for labeling tools and molecular probes used in biochemical assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific novel compounds.
• Academic Research: Utilized in university and institutional labs for methodological development and novel heterocycle chemistry.

Basic Information

Product Name	6-(2-Bromoethyl)-1,3-Dimethyl-1H-Pyrrolo[3,4-D]Pyrimidine-2,4(3H,6H)-Dione
CAS No.	841208-76-2
Molecular Formula	C₁₀H₁₂BrN₃O₂
Molecular Weight	286.13 g/mol
Synonyms	1,3-Dimethyl-6-(2-bromoethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione; 6-(2-Bromoethyl)-1,3-dimethyl-3,6-dihydro-1H-pyrrolo[3,4-d]pyrimidine-2,4-dione; 1H-Pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione, 6-(2-bromoethyl)-1,3-dimethyl-; Bromoethyl-dimethyl-pyrrolopyrimidinedione
EINECS	Contact for details

Quality Control

Every batch of 6-(2-Bromoethyl)-1,3-Dimethyl-1H-Pyrrolo[3,4-D]Pyrimidine-2,4(3H,6H)-Dione is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.