Description

4-Pyrimidinamine, 6-(1H-Imidazol-4-Yl)- (9Ci) is a heterocyclic organic compound featuring a fused pyrimidine-imidazole core structure, serving as a key advanced pharmaceutical intermediate. This compound matters for its role as a sophisticated building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery and development, especially for projects targeting kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for drug discovery programs.
• Kinase Inhibitor Research: Used as a core scaffold or precursor in the development of small-molecule kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry: Serves as a versatile intermediate for structure-activity relationship (SAR) studies and lead optimization in medicinal chemistry.
• Biochemical Research: Employed in biochemical assays and as a tool compound for studying enzyme mechanisms and cellular pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	4-Pyrimidinamine, 6-(1H-Imidazol-4-Yl)- (9Ci)
CAS No.	840529-38-6
Molecular Formula	C7H7N5
Molecular Weight	161.16 g/mol
Synonyms	6-(1H-Imidazol-4-yl)pyrimidin-4-amine; 4-Amino-6-(1H-imidazol-4-yl)pyrimidine; 6-(1H-Imidazol-4-yl)-4-pyrimidinamine; 4-Pyrimidinamine, 6-(1H-imidazol-4-yl)-; 840529-38-6; 6-(Imidazol-4-yl)pyrimidin-4-amine; 4-Amino-6-(imidazol-4-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. We implement strict in-process controls and final release testing, including identity confirmation and purity analysis via modern analytical techniques. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality management system supports the stringent requirements of pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.