Description

3-Fluoro-4-(2-Pyrrolidin-1-Yl-Ethoxy)-Phenylamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapeutics, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Biochemical Research: Serves as a tool compound for probing biological pathways and enzyme functions in laboratory settings.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke molecules for client projects.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	3-Fluoro-4-(2-Pyrrolidin-1-Yl-Ethoxy)-Phenylamine
CAS No.	837421-94-0
Molecular Formula	C12H17FN2O
Molecular Weight	224.28 g/mol
Synonyms	1-[2-[(4-Amino-2-fluorophenoxy)ethyl]pyrrolidine; 4-Amino-2-fluoro-1-[2-(1-pyrrolidinyl)ethoxy]benzene; 3-Fluoro-4-(2-(pyrrolidin-1-yl)ethoxy)aniline; 837421-94-0; Benzenamine, 3-fluoro-4-[2-(1-pyrrolidinyl)ethoxy]-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(2-Pyrrolidin-1-Yl-Ethoxy)-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.