Description

3-Fluoro-4-[4-(1-Methylethyl)-1-Piperazinyl]-Benzenamine is a high-purity, advanced pharmaceutical intermediate featuring a unique piperazine-aniline core structure. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. Pharmaceutical R&D and manufacturing teams need this material for developing new therapeutic agents, where its precise chemical architecture enables the creation of molecules with specific biological activity and improved pharmacokinetic profiles.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs).
• CNS Drug Development: Crucial precursor for research and production of potential therapeutics targeting neurological and psychiatric conditions.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug candidate efficacy and safety profiles.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.
• Process Chemistry: Employed in route scouting and scale-up optimization for efficient commercial manufacturing of target molecules.
• Reference Standard: High-purity grades are suitable for use as analytical standards in quality control laboratories.

Basic Information

Product Name	3-Fluoro-4-[4-(1-Methylethyl)-1-Piperazinyl]-Benzenamine
CAS No.	835633-79-9
Molecular Formula	C13H20FN3
Molecular Weight	237.32 g/mol
Synonyms	3-Fluoro-4-(4-isopropylpiperazin-1-yl)aniline; 1-(2-Amino-5-fluorophenyl)-4-isopropylpiperazine; 4-(4-Isopropyl-1-piperazinyl)-3-fluoroaniline; Benzenamine, 3-fluoro-4-[4-(1-methylethyl)-1-piperazinyl]-; 3-Fluoro-4-(4-isopropylpiperazin-1-yl)benzenamine; 3-Fluoro-4-(4-propan-2-ylpiperazin-1-yl)aniline
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-[4-(1-Methylethyl)-1-Piperazinyl]-Benzenamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.