Description

Ethyl 4-Chloro-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidine-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring heterocyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of novel, biologically active molecules, particularly kinase inhibitors. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with potential therapeutic value.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client drug discovery programs.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Biochemical Tool Compound: May be used to develop probes for studying specific biological pathways and enzyme functions.

Basic Information

Product Name	Ethyl 4-Chloro-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidine-7-Carboxylate
CAS No.	835632-31-0
Molecular Formula	C15H15ClN2O2S
Molecular Weight	322.81 g/mol
Synonyms	Ethyl 4-chloro-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine-7-carboxylate; 7-Carbethoxy-4-chloro-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine; 4-Chloro-7-ethoxycarbonyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine; Benzo[4,5]thieno[2,3-d]pyrimidine-7-carboxylic acid, 4-chloro-5,6,7,8-tetrahydro-, ethyl ester; CAS 835632-31-0
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidine-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.