Description

4-Methoxy-3-(2,2,2-trifluoro-ethoxymethyl)-benzaldehyde is a high-value, multi-functional aromatic aldehyde building block featuring a unique trifluoroethoxymethyl side chain. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its specific substitution pattern enables precise molecular design. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorine-containing liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The aldehyde group is a versatile handle for further functionalization via reactions like Suzuki, Heck, or reductive amination.
• Fluorine Chemistry Research: An important substrate for studying the effects of fluorine substitution on reactivity and physical properties in organic synthesis.

Basic Information

Item	Details
Product Name	4-Methoxy-3-(2,2,2-trifluoro-ethoxymethyl)-benzaldehyde
CAS No.	834913-89-2
Molecular Formula	C11H11F3O3
Molecular Weight	248.20 g/mol
Synonyms	4-Methoxy-3-((2,2,2-trifluoroethoxy)methyl)benzaldehyde; 3-((2,2,2-Trifluoroethoxy)methyl)-4-methoxybenzaldehyde; Benzaldehyde, 4-methoxy-3-((2,2,2-trifluoroethoxy)methyl)-; 834913-89-2; 4-Methoxy-3-(2,2,2-trifluoroethoxymethyl)benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxy-3-(2,2,2-trifluoro-ethoxymethyl)-benzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (NMR, IR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.