Description

4-(4-Bromo-Phenyl)-Pyrimidine-2-Thiol is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, such as herbicides and fungicides.
• Material Science Precursor: Serves as a monomer or functional unit in the development of organic electronic materials and specialty polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses producing bespoke compounds for client R&D programs.
• Academic Research: Employed in university and institutional labs for methodological development and exploring new chemical reactions involving sulfur and nitrogen heterocycles.

Basic Information

Product Name	4-(4-Bromo-Phenyl)-Pyrimidine-2-Thiol
CAS No.	832741-25-0
Molecular Formula	C10H7BrN2S
Molecular Weight	267.15 g/mol
Synonyms	2-Mercapto-4-(4-bromophenyl)pyrimidine; 4-(4-Bromophenyl)-2-pyrimidinethiol; 4-(p-Bromophenyl)-2-pyrimidinethiol; 2-Pyrimidinethiol, 4-(4-bromophenyl)-; 4-(4-Bromophenyl)pyrimidine-2-thiol; 4-(4-Bromophenyl)-2-mercaptopyrimidine; 2-Thiol-4-(4-bromophenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-(4-Bromo-Phenyl)-Pyrimidine-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.