Description

3-Bromo-5-Methyl-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its complex molecular architecture, featuring bromo, methyl, and trifluoromethyl substituents on a pyrazolopyrimidine core, makes it a critical intermediate for developing novel active compounds. This product is essential for R&D and production teams in the pharmaceutical and agrochemical sectors seeking to introduce specific steric and electronic properties into their target molecules. Its carboxylic acid functionality provides a versatile handle for further derivatization and coupling reactions.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging the bioactivity of the pyrazolopyrimidine scaffold.
• Material Science: Acts as a building block for creating specialty chemicals and functional materials with tailored properties.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, fluorinated heterocycles.
• Academic & Industrial R&D: Used in discovery chemistry programs to explore new chemical space and structure-activity relationships (SAR).

Basic Information

Product Name	3-Bromo-5-Methyl-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	832740-70-2
Molecular Formula	C9H5BrF3N3O2
Molecular Weight	324.06 g/mol
Synonyms	3-Bromo-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 832740-70-2; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 3-bromo-5-methyl-7-(trifluoromethyl)-; 3-Bromo-5-methyl-7-trifluoromethyl-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to a robust quality management system to guarantee the reliability and traceability required for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.