Description

4-Difluoromethoxy-3-Ethoxy-Phenylamine is a high-purity aromatic amine derivative featuring both difluoromethoxy and ethoxy substituents, making it a versatile and valuable building block in advanced organic synthesis. Its unique structure provides critical reactivity for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific fluorinated and alkoxy motifs into their target molecules.

Application

• Key synthetic intermediate in the research and development of novel pharmaceutical compounds, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Precursor for the synthesis of advanced agrochemicals, including herbicides and fungicides, where the difluoromethoxy group can enhance biological activity and metabolic stability.
• Building block for functional materials and liquid crystals, where its aromatic core and substituents influence electronic properties and mesophase behavior.
• Used in organic light-emitting diode (OLED) research as a component in the synthesis of electron-transport or host materials.
• Intermediate in dye and pigment chemistry for creating specialized colorants with improved properties.
• Starting material for custom synthesis and contract manufacturing organizations (CMOs) serving the life sciences industry.

Basic Information

Product Name	4-Difluoromethoxy-3-Ethoxy-Phenylamine
CAS No.	832740-41-7
Molecular Formula	C9H11F2NO2
Molecular Weight	203.19 g/mol
Synonyms	3-Ethoxy-4-(difluoromethoxy)aniline; 4-Amino-2-ethoxy-1-(difluoromethoxy)benzene; 1-(Difluoromethoxy)-2-ethoxy-4-aminobenzene; 2-Ethoxy-4-(difluoromethoxy)aniline; 4-(Difluoromethoxy)-3-ethoxyaniline; Benzenamine, 3-ethoxy-4-(difluoromethoxy)-; 832740-41-7
EINECS	Contact for details

Quality Control

Our 4-Difluoromethoxy-3-Ethoxy-Phenylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.