Description

4-(3,5-Dichloro-Phenyl)-Pyrimidine-2-Thiol is a high-purity, heterocyclic organic compound primarily utilized as a sophisticated chemical intermediate in advanced synthesis. This compound matters for its role as a critical building block in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pyrimidine-thiol core enables precise molecular modifications. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or ligand in the creation of functional polymers and metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds.

Basic Information

Product Name	4-(3,5-Dichloro-Phenyl)-Pyrimidine-2-Thiol
CAS No.	832739-73-8
Molecular Formula	C10H6Cl2N2S
Molecular Weight	257.14 g/mol
Synonyms	2-Mercapto-4-(3,5-dichlorophenyl)pyrimidine; 4-(3,5-Dichlorophenyl)-2-pyrimidinethiol; 4-(3,5-Dichlorophenyl)pyrimidine-2-thiol; 2(1H)-Pyrimidinethione, 4-(3,5-dichlorophenyl)-; 4-(3,5-Dichlorophenyl)-2-mercaptopyrimidine; 2-Pyrimidinethiol, 4-(3,5-dichlorophenyl)-; 4-(3,5-Dichlorophenyl)-2-thiopyrimidone
EINECS	Contact for details

Quality Control

Our 4-(3,5-Dichloro-Phenyl)-Pyrimidine-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.