Description

3-(2,2-Difluoroethoxy)-5-Nitroaniline is a specialized aromatic amine derivative featuring a difluoroethoxy substituent and a nitro group. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, valued for its unique fluorine-containing moiety which can impart desirable metabolic stability and bioavailability to target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders or possessing fluorinated pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the difluoroethoxy group can enhance biological activity and environmental persistence.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the construction of complex heterocyclic compounds.
• Material Science Research: Potential monomer or modifier in the development of specialty polymers and advanced materials with specific optical or electronic properties.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing specialized azo dyes and pigments, leveraging its nitro and amine functional groups.

Basic Information

Product Name	3-(2,2-Difluoroethoxy)-5-Nitroaniline
CAS No.	832738-23-5
Molecular Formula	C8H8F2N2O3
Molecular Weight	218.16 g/mol
Synonyms	5-Nitro-3-(2,2-difluoroethoxy)aniline; 3-Amino-5-(2,2-difluoroethoxy)nitrobenzene; 2,2-Difluoroethyl 3-amino-5-nitrophenyl ether; 3-(2,2-Difluoroethoxy)-5-nitrobenzenamine; Aniline, 3-(2,2-difluoroethoxy)-5-nitro-
EINECS	Contact for details

Quality Control

Our 3-(2,2-Difluoroethoxy)-5-Nitroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent composition. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting identity, purity, and impurity profiles to support your regulatory compliance and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to prevent decomposition.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.