Description

2-Hydrazino-4-Thien-2-Yl-6-(Trifluoromethyl)Pyrimidine is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its multifunctional molecular architecture, which incorporates a reactive hydrazino group, a thiophene ring, and a trifluoromethyl-substituted pyrimidine core, enabling the construction of complex, biologically active molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance metabolic stability and bioavailability.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as organic semiconductors or light-emitting materials, due to its conjugated thiophene-pyrimidine system.
• Chemical Biology & Proteomics: Utilized as a reactive handle in the design of chemical probes and affinity tags for studying protein function and interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	2-Hydrazino-4-Thien-2-Yl-6-(Trifluoromethyl)Pyrimidine
CAS No.	832737-83-4
Molecular Formula	C9H6F3N5S
Molecular Weight	273.24 g/mol
Synonyms	2-Hydrazinyl-4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidine; 4-(2-Thienyl)-6-(trifluoromethyl)-2-pyrimidinylhydrazine; 2-Hydrazino-4-(2-thienyl)-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-4-(thiophen-2-yl)pyrimidin-2-ylhydrazine; 2-Hydrazino-4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidine; 4-(Thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylhydrazine
EINECS	Contact for details

Quality Control

Our 2-Hydrazino-4-Thien-2-Yl-6-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original packaging.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.