Description

4-(5-Bromopyrimidin-2-Yloxy)Piperidine-1-Carboxylic Acid tert-Butyl is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• API Development: Serves as a precursor in the multi-step synthesis of final Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Chemical Biology: Employed in the design and synthesis of chemical probes for target validation and biological pathway studies.

Basic Information

Product Name	4-(5-Bromopyrimidin-2-Yloxy)Piperidine-1-Carboxylic Acid tert-Butyl
CAS No.	832735-41-8
Molecular Formula	C14H20BrN3O3
Molecular Weight	358.23 g/mol
Synonyms	1-Boc-4-(5-bromopyrimidin-2-yloxy)piperidine; tert-Butyl 4-((5-bromopyrimidin-2-yl)oxy)piperidine-1-carboxylate; 4-(5-Bromo-2-pyrimidinyloxy)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-[(5-bromo-2-pyrimidinyl)oxy]-1-piperidinecarboxylate; 4-(5-Bromopyrimidin-2-yloxy)piperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(5-bromo-2-pyrimidyloxy)piperidine; 832735-41-8
EINECS	Contact for details

Quality Control

Our 4-(5-Bromopyrimidin-2-Yloxy)Piperidine-1-Carboxylic Acid tert-Butyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.